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Microbial landscape in the neonatal care intensive unit

https://doi.org/10.37489/2588-0519-2024-3-93-95

EDN: LOQHNQ

Abstract

Improvement of the clinical outcomes of newborns with hospital-acquired infections requires microbiological monitoring to ensure timely initiation of appropriate empirical therapy. In our study we investigated the patterns of pathogens responsible for hospital-acquired infections in neonatal intensive care units and assessed the levels of antibiotic resistance among these pathogens. The study included 4,891 samples from newborns. Gram — positive microflora was found in 55.9% of the samples and gram-negative — in 44.1%. The antibiotic resistance profile revealed high resistance to penicillin-based antibiotics among staphylococci. Gram-negative microorganisms remained sensitive to most antibacterial drugs.

About the Authors

A. A. Gorbacheva
Peoples' Friendship University of Russia named after Patrice Lumumba
Russian Federation

Anastasia A. Gorbacheva  — Postgraduate student of the Department of General and Clinical Pharmacology

Moscow



O. I. Butranova
Peoples' Friendship University of Russia named after Patrice Lumumba
Russian Federation

Olga  I.  Butranova  — PhD, Cand. Sci. (Med), Associate Professor of the Department of General and Clinical Pharmacology

Moscow



References

1. Mariani M, Bandettini R, LA Masa D, et al. Bacterial invasive infections in a neonatal intensive care unit: a 13 years microbiological report from an Italian tertiary care centre. J Prev Med Hyg. 2020 Jul 4;61(2):E162-E166. doi: 10.15167/2421-4248/jpmh2020.61.2.1401.

2. Shabanova NE, Model GYu, Ni OG, et al. The comparative analysis of microbiological monitoring in neonatal intensive care units in Krasnodar Regional Clinical Hospital №2. Kubanskij nauchnyj medicinskij vestnik. 2018; 25(3): 125- 128. (In Russ.)doi: 10.25207/1608-6228-2018-25-3-125-128.

3. Mariani M, Parodi A, Minghetti D, et al. Early and Late Onset Neonatal Sepsis: Epidemiology and Effectiveness of Empirical Antibacterial Therapy in a III Level Neonatal Intensive Care Unit. Antibiotics (Basel). 2022 Feb 21;11(2):284. doi: 10.3390/antibiotics11020284.


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For citations:


Gorbacheva A.A., Butranova O.I. Microbial landscape in the neonatal care intensive unit. Kachestvennaya Klinicheskaya Praktika = Good Clinical Practice. 2024;(3):93-95. (In Russ.) https://doi.org/10.37489/2588-0519-2024-3-93-95. EDN: LOQHNQ

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ISSN 2588-0519 (Print)
ISSN 2618-8473 (Online)