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Rationality of routine clinical use of olokizumab in COVID-19

https://doi.org/10.37489/2588-0519-2020-S4-68-70

Abstract

Routine clinical use of olokizumab in COVID-19 is not recommended. The use of olokizumab is possible in clinical trials.

About the Authors

V. M. Tsvetov
Federal Center for Cardiovascular Surgery of the Ministry of Health of Russia
Russian Federation

Tsvetov Vitaly M. – Candidate of Medical Sciences, Doctor — Clinical Pharmacologist. SPIN code: 3202-7659

Chelyabinsk



A. V. Matveev
Russian Medical Academy of Continuing Professional Education of the Ministry of Health of Russia
Russian Federation

Matveev Alexander V. – Candidate of Medical Sciences, Associate Professor of the Department of Clinical Pharmacology and Therapy. SPIN code: 8518-1320

Moscow



D. A. Sychev
Russian Medical Academy of Continuing Professional Education of the Ministry of Health of Russia
Russian Federation

Sychev Dmitry A. – Doctor of Medical Sciences, Professor, Corresponding Member RAS, Rector, Head Department of Clinical Pharmacology and Therapy. SPIN code: 4525-7556

Moscow



References

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2. U.S. Pharmacopeia [Internet]. [cited 28.05.2020]; Available from: https://www.usp.org/

3. E.U. Pharmacopeia [Internet]. [cited 28.05.2020]; Available from: https://www.edqm.eu/en/european-pharmacopoeia-ph-eur-10th-edition

4. https://clinicaltrials.gov/ct2/show/NCT04380519?cond=Olokizumab&draw=2&rank=7

5. Russell B, Moss C, George G et al. Associations between immunesuppressive and stimulating drugs and novel COVID-19-a systematic review of current evidence. Ecancermedicalscience. 2020 Mar 27;14:1022. DOI: 10.3332/ecancer.2020.1022

6. Choy EH, De Benedetti F, Takeuchi T et al. Translating IL-6 biology into effective treatments. Nat Rev Rheumatol. 2020 Jun;16(6):335-345. DOI: 10.1038/s41584-020-0419-z

7. Magro G. SARS-CoV-2 and COVID-19: is interleukin-6 (IL-6) the ‘culprit lesion’ of ARDS onset? What is there besides Tocilizumab? SGP130Fc. Cytokine X. 2020 Jun;2(2):100029. DOI: 10.1016/j.cytox.2020.100029

8. Temporary guidelines of the Ministry of health of the Russian Federation. Prevention, diagnosis and treatment of new coronavirus infection (COVID-19) (In Russ). Доступно по: https://static-1.rosminzdrav.ru/system/attachments/attaches/000/050/122/original/28042020_%D0%9CR_COVID-19_v6.pdf Ссылка активна на 28.05.2020


Review

For citations:


Tsvetov V.M., Matveev A.V., Sychev D.A. Rationality of routine clinical use of olokizumab in COVID-19. Kachestvennaya Klinicheskaya Praktika = Good Clinical Practice. 2020;(4S):68-70. (In Russ.) https://doi.org/10.37489/2588-0519-2020-S4-68-70

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ISSN 2588-0519 (Print)
ISSN 2618-8473 (Online)