Use of etiotropic and pathogenetic medicines for COVID-19 in patients with renal failure and/or on dialysis
https://doi.org/10.37489/2588-0519-2020-S4-39-46
Abstract
Impaired kidney function may influence pharmacokinetics of most of the drugs, including the ones used in COVID-19. In this publication, the most important pharmacokinetic parameters and dose adjustment approaches are provided, based on The Renal Drug Handbook и Sanford Guide. In the majority of cases, mild kidney function reduction does not necessitate dose adjustment. Each case should be considered individually, measuring benefits against risks.
About the Authors
V. M. Tsvetov
Federal Center for Cardiovascular Surgery of the Ministry of Health of Russia
Russian Federation
Russian Federation
Tsvetov Vitaly M. – Candidate of Medical Sciences, Doctor — Clinical Pharmacologist. SPIN code: 3202-7659
Chelyabinsk
I. N. Sychev
Russian Medical Academy of Continuing Professional Education of the Ministry of Health of Russia; State budgetary institution of health care of the Clinical hospital named after S. S. Yudin of the Moscow city department of health care
Russian Federation
Russian Federation
Sychev Igor N. – Candidate of Medical Sciences, Associate Professor of the Department of Clinical Pharmacology and Therapy, Russian Medical Academy of Continuing Professional Education, Ministry of Health of Russia, Russia, Moscow; Head Department of clinical pharmacology State budgetary institution of health care of Moscow «City clinical hospital named after S. S. Yudin of the department of health care of Moscow». SPIN code: 7282-6014
Moscow
D. A. Sychev
Russian Medical Academy of Continuing Professional Education of the Ministry of Health of Russia
Russian Federation
Russian Federation
Sychev Dmitry A. – Doctor of Medical Sciences, Professor, Corresponding Member RAS, Rector, Head Department of Clinical Pharmacology and Therapy. SPIN code: 4525-7556
Moscow
References
1. Temporary guidelines of the Ministry of health of the Russian Federation for the prevention, diagnosis and treatment of new coronavirus infection (COVID-19). Version 6 (08.04.2020). (In Russ). Доступно по: https://clck.ru/NCM6x Ссылка активна на 15.05.2020.
2. The Renal Drug Handbook (5 издание). https://renaldrugdatabase.com
3. Sanford Guide. https://webedition.sanfordguide.com
4. Государственный реестр [П N012097/01] https://clck.ru/REFRQ
5. Государственный реестр [ЛП-005185] https://clck.ru/REFSP
6. Clinical pharmacokinetics: theoretical, applied and analytical aspects: guidelines. Ed by V.G. Kukes. Moscow: GEOTAR-Media; 2009. (In Russ).
7. Stetsyuk E.A. Fundamentals of dialysis. Moscow: GEOTAR-Media; 2001. (In Russ).
Review
For citations:
Tsvetov V.M., Sychev I.N., Sychev D.A. Use of etiotropic and pathogenetic medicines for COVID-19 in patients with renal failure and/or on dialysis. Kachestvennaya Klinicheskaya Praktika = Good Clinical Practice. 2020;(4S):39-46. (In Russ.) https://doi.org/10.37489/2588-0519-2020-S4-39-46
Views:
1018
Email this article 