Analysis of the effectiveness of acne drug therapy

Relevance. Acne is one of the most common dermatological diseases, affecting a significant proportion of the population, particularly adolescents and young adults. The modern pharmaceutical market offers several drugs for acne treatment, including topical retinoids, antibiotics, benzoyl peroxide, and azelaic acid, as well as systemic drugs, such as isotretinoin and hormonal agents. The growing problem of antibiotic resistance among microorganisms, including Propionibacterium acnes, requires rational antibacterial drug use and alternative acne treatment methods.

Objective. A comprehensive analysis of the effectiveness of various methods of acne drug therapy to optimize treatment approaches and improve therapy results.

Methods. As part of this review study, a comprehensive analysis of the scientific literature on acne drug therapy was conducted. The inclusion criteria were original studies, meta-analyses, and systematic reviews published over the past 5 years (2018–2023).

Results. An analysis of the literature has shown that topical retinoids and antibiotics, as well as systemic retinoids and antibiotics, remain the most effective methods of treating acne.

Conclusion. The analysis of the modern scientific literature confirms the effectiveness of existing methods of drug therapy for acne. The choice of optimal therapy should be based on the individual characteristics of the patient, the severity of the disease and the presence of concomitant factors.

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