clinvestКачественная клиническая практикаKachestvennaya Klinicheskaya Praktika = Good Clinical Practice2588-05192618-8473ООО «Издательство ОКИclinvest-45Research ArticleКЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯCLINICAL TRIALSОценка исходов пациентами в клинических исследованияхPatient-reported outcomes in clinical studiesЛеоноваМ. В.LeonovaM. V.anti23@mail.ruФГБОУ ВП РНИМУ им. Н.И. Пирогова Минздрава РоссииРоссияRussian National Research Medical University named after N.I. PirogovRussian Federation201616052018023845Copyright © Леонова М.В., 20182018Леонова М.В.Leonova M.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.clinvest.ru/jour/article/view/45

Представлен обзор по использованию исходов лечения, оцениваемых пациентами patient-reported outcomes - PRO) в клинических исследованиях: концепция и содержание PRO, методология включения PRO в клинические исследования, этапы создания и разработки, основные виды и формы инструментов PRO, психометрические характеристики инструментов PRO (валидация, чувствительность, надёжность), техника проведения оценок PRO.

A review on the use of patient-reported outcomes (PRO) in clinical studies: the concept and content of the PRO, methodology enable PRO in clinical studies, the stages of creation and development, basic types and forms of PRO instruments, psychometric characteristics of the instruments PRO (validation, sensitivity, reliability) of PRO assessment technique.

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The authors declare that there are no conflicts of interest present.