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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">clinvest</journal-id><journal-title-group><journal-title xml:lang="ru">Качественная клиническая практика</journal-title><trans-title-group xml:lang="en"><trans-title>Kachestvennaya Klinicheskaya Praktika = Good Clinical Practice</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2588-0519</issn><issn pub-type="epub">2618-8473</issn><publisher><publisher-name>ООО «Издательство ОКИ</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">clinvest-399</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ФАРМАКОЭКОНОМИКА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PHARMACOECONOMICS</subject></subj-group></article-categories><title-group><article-title>Клинико-экономическое сравнение инсулина гларгин и инсулина премикс аспарт при сахарном диабете типа 2</article-title><trans-title-group xml:lang="en"><trans-title></trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Колбин</surname><given-names>А. С.</given-names></name></name-alternatives><bio xml:lang="ru"><p>медицинский факультет</p></bio><email xlink:type="simple">clinvest@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Первый Санкт-Петербургский государственный медицинcкий университет имени акад. И.П.Павлова; Санкт-Петербургский государственный университет</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2009</year></pub-date><pub-date pub-type="epub"><day>06</day><month>07</month><year>2018</year></pub-date><volume>0</volume><issue>2</issue><fpage>1</fpage><lpage>9</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Колбин А.С., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Колбин А.С.</copyright-holder><copyright-holder xml:lang="en">Колбин А.С.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.clinvest.ru/jour/article/view/399">https://www.clinvest.ru/jour/article/view/399</self-uri><abstract><p>Результаты. Инсулин гларгин по результатам несравнительных рандомизированных клинических исследований в сопоставимых группах больных СД 2 имеет меньшие дозировки для достижения компенсации, что в совокупности с меньшими дополнительными расходами на средства введения и контроля, оборачивается реальной экономической выгодой от применения в сравнении с инсулином аспарт 30/70 (при этом учтены и затраты на пероральные сахароснижающие средства). Инсулин гларгин в режиме базально-болюсной терапии СД 2 в сочетании с инсулином глулизин по результатам клинических исследований экономичнее, чем инсулин аспарт 30/70, имея прогнозную стоимость компенсации в течение года на 57,6% меньше. Исследования реальной практики при тождественности дозировок свидетельствуют об экономических преимуществах инсулина гларгин перед инсулином аспарт 30/70, возникающих как вследствие его лучшей клинической эффективности, так и меньшей потребности в расходных материалах.</p></abstract><kwd-group xml:lang="ru"><kwd>фармакоэкономика</kwd><kwd>инсулин гларгин</kwd><kwd>инсулин премикс аспарт</kwd><kwd>сахарный диабет 2 типа</kwd><kwd>анализ затраты-эффективность</kwd><kwd>NNT-анализ</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">UKPDS Group. Intensive blood glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33) // Lancet 1998; 352: 837–853.</mixed-citation><mixed-citation xml:lang="en">UKPDS Group. 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