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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">clinvest</journal-id><journal-title-group><journal-title xml:lang="ru">Качественная клиническая практика</journal-title><trans-title-group xml:lang="en"><trans-title>Kachestvennaya Klinicheskaya Praktika = Good Clinical Practice</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2588-0519</issn><issn pub-type="epub">2618-8473</issn><publisher><publisher-name>ООО «Издательство ОКИ</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">clinvest-340</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НОВЫЕ ЛЕКАРСТВЕННЫЕ СРЕДСТВА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>NEW DRUGS AND HEALTH TECHNOLOGIES</subject></subj-group></article-categories><title-group><article-title>Разработка систем доставки лекарственных средств с применением микро- и наночастиц</article-title><trans-title-group xml:lang="en"><trans-title></trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Соснов</surname><given-names>А. В.</given-names></name></name-alternatives><email xlink:type="simple">clinvest@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иванов</surname><given-names>Р. В.</given-names></name></name-alternatives><email xlink:type="simple">clinvest@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Балакин</surname><given-names>К. В.</given-names></name></name-alternatives><email xlink:type="simple">clinvest@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шоболов</surname><given-names>Д. Л.</given-names></name></name-alternatives><email xlink:type="simple">clinvest@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Федотов</surname><given-names>Ю. А.</given-names></name></name-alternatives><email xlink:type="simple">clinvest@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Калмыков</surname><given-names>Ю. М.</given-names></name></name-alternatives><email xlink:type="simple">clinvest@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Исследовательский Институт Химического Разнообразия, Химки, Московская обл.</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-2"><institution>«Технология лекарств», Химки, Московская обл.</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-3"><institution>Исследовательский Институт Химического Разнообразия (ИИХР), Московская область, г. Химки</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2008</year></pub-date><pub-date pub-type="epub"><day>28</day><month>06</month><year>2018</year></pub-date><volume>0</volume><issue>2</issue><fpage>4</fpage><lpage>12</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Соснов А.В., Иванов Р.В., Балакин К.В., Шоболов Д.Л., Федотов Ю.А., Калмыков Ю.М., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Соснов А.В., Иванов Р.В., Балакин К.В., Шоболов Д.Л., Федотов Ю.А., Калмыков Ю.М.</copyright-holder><copyright-holder xml:lang="en">Соснов А.В., Иванов Р.В., Балакин К.В., Шоболов Д.Л., Федотов Ю.А., Калмыков Ю.М.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.clinvest.ru/jour/article/view/340">https://www.clinvest.ru/jour/article/view/340</self-uri><abstract/><kwd-group xml:lang="ru"><kwd>системы доставки лекарственных средств</kwd><kwd>микрочастицы</kwd><kwd>наночастицы</kwd><kwd>нанотехнологии</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Dutta R.C. Drug carriers in pharmaceutical design: promises and progress. Curr. Pharm. Des. 2007; 13: 7: 761-769.</mixed-citation><mixed-citation xml:lang="en">Dutta R.C. Drug carriers in pharmaceutical design: promises and progress. Curr. Pharm. Des. 2007; 13: 7: 761-769.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Caruthers S.D., Wickline S.A., Lanza G.M. Nanotechnological applications in medicine. Curr. Opin. Biotechnol. 2007; 18: 1: 26-30.</mixed-citation><mixed-citation xml:lang="en">Caruthers S.D., Wickline S.A., Lanza G.M. Nanotechnological applications in medicine. Curr. Opin. Biotechnol. 2007; 18: 1: 26-30.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Euliss L.E., DuPont J.A., Gratton S., DeSimone J. Imparting size, shape, and composition control of materials for nanomedicine. Chem. Soc. Rev. 2006; 35: 11: 1095-104.</mixed-citation><mixed-citation xml:lang="en">Euliss L.E., DuPont J.A., Gratton S., DeSimone J. Imparting size, shape, and composition control of materials for nanomedicine. Chem. Soc. Rev. 2006; 35: 11: 1095-104.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Medvedeva N.V., Ipatova O.M., Ivanov Iu.D. et al. Nanobiotechnology and nanomedicine. Biomed Khim. 2006; 52: 6: 529-546.</mixed-citation><mixed-citation xml:lang="en">Medvedeva N.V., Ipatova O.M., Ivanov Iu.D. et al. Nanobiotechnology and nanomedicine. Biomed Khim. 2006; 52: 6: 529-546.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Leoni L., Desai T.A. Nanoporous biocapsules for the encapsulation of insulinoma cells: biotransport and biocompatibility considerations. IEEE Trans. Biomed. Eng. 2001; 48: 11: 1335-1341.</mixed-citation><mixed-citation xml:lang="en">Leoni L., Desai T.A. Nanoporous biocapsules for the encapsulation of insulinoma cells: biotransport and biocompatibility considerations. IEEE Trans. Biomed. Eng. 2001; 48: 11: 1335-1341.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Onishi H., Machida Y. Macromolecular and nanotechnological modification of camptothecin and its analogs to improve the efficacy. Curr. Drug Discov. Technol. 2005; 2: 3: 169-183.</mixed-citation><mixed-citation xml:lang="en">Onishi H., Machida Y. Macromolecular and nanotechnological modification of camptothecin and its analogs to improve the efficacy. Curr. Drug Discov. Technol. 2005; 2: 3: 169-183.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Kazakov S., Levon K. Liposome-nanogel structures for future pharmaceutical applications. Curr. Pharm. Des. 2006; 12: 36: 4713-4728.</mixed-citation><mixed-citation xml:lang="en">Kazakov S., Levon K. Liposome-nanogel structures for future pharmaceutical applications. Curr. Pharm. Des. 2006; 12: 36: 4713-4728.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Bai S., Thomas C., Rawat A., Ahsan F. Recent progress in dendrimer-based nanocarriers. Crit. Rev. Ther. Drug Carrier Syst. 2006; 23: 6: 437-495.</mixed-citation><mixed-citation xml:lang="en">Bai S., Thomas C., Rawat A., Ahsan F. Recent progress in dendrimer-based nanocarriers. Crit. Rev. Ther. Drug Carrier Syst. 2006; 23: 6: 437-495.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Torchilin V.P. Micellar nanocarriers: pharmaceutical perspectives. Pharm. Res. 2007; 24: 1: 1-16.</mixed-citation><mixed-citation xml:lang="en">Torchilin V.P. Micellar nanocarriers: pharmaceutical perspectives. Pharm. Res. 2007; 24: 1: 1-16.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Sakaguchi H., Serizawa T., Akashi M. Preparation and characterization of stimuli-resistible hydrogels nano-coated with polyelectrolyte multilayer films. J. Nanosci. Nanotechnol. 2006; 6: 4: 1124-1127.</mixed-citation><mixed-citation xml:lang="en">Sakaguchi H., Serizawa T., Akashi M. Preparation and characterization of stimuli-resistible hydrogels nano-coated with polyelectrolyte multilayer films. J. Nanosci. Nanotechnol. 2006; 6: 4: 1124-1127.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Nahar M., Dutta T., Murugesan S. et al. Functional polymeric nanoparticles: an efficient and promising tool for active delivery of bioactives. Crit. Rev. Ther. Drug Carrier Syst. 2006; 23: 4: 259-318.</mixed-citation><mixed-citation xml:lang="en">Nahar M., Dutta T., Murugesan S. et al. Functional polymeric nanoparticles: an efficient and promising tool for active delivery of bioactives. Crit. Rev. Ther. Drug Carrier Syst. 2006; 23: 4: 259-318.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Zakharian T.Y., Seryshev A., Sitharaman B. et al. A fullerene-paclitaxel chemotherapeutic: synthesis, characterization, and study of biological activity in tissue culture. J. Am. Chem. Soc. 2005; 127: 36: 12508-12509.</mixed-citation><mixed-citation xml:lang="en">Zakharian T.Y., Seryshev A., Sitharaman B. et al. A fullerene-paclitaxel chemotherapeutic: synthesis, characterization, and study of biological activity in tissue culture. J. Am. Chem. Soc. 2005; 127: 36: 12508-12509.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Ebbesen M., Jensen T.G. Nanomedicine: techniques, potentials, and ethical implications. J. Biomed. Biotechnol. 2006; 2006: 5: 51516.</mixed-citation><mixed-citation xml:lang="en">Ebbesen M., Jensen T.G. Nanomedicine: techniques, potentials, and ethical implications. J. Biomed. Biotechnol. 2006; 2006: 5: 51516.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Pelkmans L., Fava E., Grabner H. et al. Genome-wide analysis of human kinases in clathrin- and caveolae/raft-mediated endocytosis. Nature 2005; 436: 78-86.</mixed-citation><mixed-citation xml:lang="en">Pelkmans L., Fava E., Grabner H. et al. Genome-wide analysis of human kinases in clathrin- and caveolae/raft-mediated endocytosis. Nature 2005; 436: 78-86.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Geng F., Shen Y., Peng B. et al. Visualization and characterization of drug carrier transportation and distribution in vivo. Conf. Proc. IEEE Eng. Med. Biol. Soc. 2005; 1: 508-11.</mixed-citation><mixed-citation xml:lang="en">Geng F., Shen Y., Peng B. et al. Visualization and characterization of drug carrier transportation and distribution in vivo. Conf. Proc. IEEE Eng. Med. Biol. Soc. 2005; 1: 508-11.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Manabe N., Hoshino A., Liang Y.Q. et al. Quantum dot as a drug tracer in vivo. IEEE Trans. Nanobioscience. 2006; 5: 4: 263-267.</mixed-citation><mixed-citation xml:lang="en">Manabe N., Hoshino A., Liang Y.Q. et al. Quantum dot as a drug tracer in vivo. IEEE Trans. Nanobioscience. 2006; 5: 4: 263-267.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
